An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.
Jamie Oliver and his good mate Tobie Puttock are opening the first Fifteen restaurant in Australia. To prove their conviction that it's a passion for food and not academic qualifications that makes a good cook, they are training a group of 16-24 year old disadvantaged Australians, with the Fifteen Foundation, to work as chefs in the kitchen of the new Melbourne restaurant.
Melinda helps Ned deal with a ghost who had just put a scare into him. Melinda also helps a ghost who appears without any clothes on. Delia sees that Melinda is once again talking to herself and Melinda decides to share her gift with Delia.
Castle and Beckett investigate the bizarre murder of a young woman who was found ritually posed. When the team finds a collection of strange symbols in her apartment, Castle becomes convinced they’ve stumbled onto a 'Da Vinci Code' style conspiracy.
Castle and Beckett help Alexis with an Innocence Review case. With only 72 hours until his execution, their goal is to prove that the death row inmate was wrongly convicted. But, some of what they uncover may only strengthen the case against him.
Meredith, Derek, Cristina and Arizona receive big news regarding the plane crash lawsuit, Richard avoids Catherine's romantic advances and Jackson takes on one of Mark Sloane's old patients. Meanwhile, Derek begins recovery on his hand.
A new medical professional enters the hospital, Arizona struggles with the emotional and physical pain of a phantom limb, and while battling pregnancy hormones, an overly-emotional Meredith is confronted with her worst fear.
As Derek and April work around the clock to find a solution for the hospital, Cristina struggles to respect the wishes of a family whose son is dying. Meanwhile, Arizona empathizes with a teenager who faces problems similar to her own.